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ea0070ep385 | Reproductive and Developmental Endocrinology | ECE2020

Hyperandrogenism caused by a leydig cell tumor of the ovary: A case report

Mendonça Fernando , Souto Selma , Magalhães Daniela , Fernandes Ana Sofia , Coelho Ana Rita , Portugal Raquel , Falcão Vera , Tavares Sara , Beires Jorge , Carvalho Davide

Introduction: Leydig stromal cell tumors are a subtype of steroid tumors that make up to less than 0.1% of the ovarian tumors. These neoplasms can affect women from all ages but are more frequent after menopause, being usually unilateral, benign and small sized. In around 75% of cases, these tumors produce androgenic hormones, causing oligomenorrhea and virilization.Case report: A 39-year-old woman, nulligravid, with complains regarding androgenic alopec...

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ea0070aep600 | Pituitary and Neuroendocrinology | ECE2020

Phenotypic differences between patients with familial pituitary neuroendocrine tumours due to MEN1 or AIP mutations

Marques Pedro , Magalhães Daniela , Caimari Francisca , Hernández Ramírez Laura , Collier David , Lim Chung , Stals Karen , Ellard Sian , Druce Maralyn , Akker Scott , Waterhouse Mona , Drake William , Grossman Ashley B. , Korbonits Marta

Introduction: Germline AIP and MEN1 mutations are the main known aetiologies of familial pituitary neuroendocrine tumours (PitNETs), which represent 5% of all PitNETs. We compared the clinical and tumour characteristics of AIP (AIP mut) and MEN1 mutation-positive (MEN1 mut) PitNET patients.Methods: We retrospectively analysed 70 MEN1 mut and 167 AIP mut patients with PitNETs. MEN...

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Endocrine Abstracts

Hyperandrogenism caused by a leydig cell tumor of the ovary: A case report

Phenotypic differences between patients with familial pituitary neuroendocrine tumours due to MEN1 or AIP mutations

BiosciAbstracts